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1.
Arch. argent. pediatr ; 122(1): e202202975, feb. 2024. tab
Article in English, Spanish | LILACS, BINACIS | ID: biblio-1524319

ABSTRACT

Introducción. La evaluación de la condición física (CF), junto con otros indicadores de salud, es una estrategia utilizada para conocer el estado actual de los escolares. El principal objetivo fue medir en escolares sanluiseños el estado de salud actual, los niveles de CF y construir tablas de referencias de CF. Población y métodos. Escolares entre 9 y 12 años de edad (ambos sexos) fueron evaluados con dos indicadores de salud: índice de masa corporal y presión arterial. La CF fue medida con la batería ALPHA-Fitness. El orden de las pruebas fue el siguiente: tensión arterial, masa corporal, estatura, longitud de pie y mano, salto en longitud, velocidad en 30 metros, agilidad 4 × 10 m y la prueba de ida y vuelta en 20 metros. Se calculó el índice de masa corporal (IMC) y la maduración biológica. Resultados. Fueron evaluados 15548 escolares. Los valores promedios fueron presión arterial sistólica 101 ± 10 mmHg y diastólica 66 ± 7 mmHg; IMC 20,2 ± 4,3 kg/m2. Para la CF fueron las siguientes: componente cardiorrespiratorio VO2 máx. 39,87 ± 3,2 ml/kg/min y velocidad alcanzada en la prueba de ida y vuelta en 20 m 8,9 ± 0,6 km/h; componente neuromuscular; salto en longitud: 120,6 ± 23,9 cm, velocidad 30 m: 6,56 ± 0,85 s, agilidad 4 × 10 m: 15,17 ± 1,82 s. El rendimiento siempre fue superior en el grupo masculino (p <0,001). Conclusión. Los escolares mostraron niveles saludables de presión arterial. El 50 % de la muestra fue clasificada con sobrepeso u obesidad según el IMC. En ambos sexos, se observaron bajos niveles de CF. Por primera vez, se elaboraron tablas de referencia de CF en escolares sanluiseños


Introduction. The assessment of physical fitness (PF), is useful strategy to know the current status of schoolchildren. Our primary objective was to measure the current health status and PF levels of schoolchildren in San Luis and to develop PF reference tables. Population and methods. Schoolchildren aged 9 to 12 years (boys and girls) were assessed based on 2 health indicators: body mass index and blood pressure. PF was measured using the ALPHA-Fitness test battery. Blood pressure, body mass, height, foot and hand length, standing long jump, 30 m sprint, 4 × 10 m agility test, and 20 m shuttle run test were assessed. The body mass index (BMI) and biological maturation were estimated. Results. A total of 15 548 schoolchildren were assessed. Average systolic blood pressure was 101 ± 10 mmHg and diastolic blood pressure, 66 ± 7 mmHg; BMI: 20.2 ± 4.3 kg/m2. Average PF was, in the cardiorespiratory component, VO2 max.: 39.87 ± 3.2 mL/kg/min and speed reached during the 20 m shuttle run test: 8.9 ± 0.6 km/h; in the musculoskeletal component, standing long jump: 120.6 ± 23.9 cm, 30 m sprint: 6.56 ± 0.85 s, 4 × 10 m agility test: 15.17 ± 1.82 s. The performance was better in the boys group (p < 0.001). Conclusion. Blood pressure was normal. Fifty percent of the sample was overweight or obese as per their BMI. Both boys and girls showed low PF levels. PF reference tables for schoolchildren from San Luis were developed for the first time.


Subject(s)
Humans , Male , Female , Child , Physical Fitness/psychology , Exercise Test , Argentina , Exercise/psychology , Body Mass Index , Cross-Sectional Studies
2.
Evid. actual. práct. ambul. (En línea) ; 27(1): e007089, 2024. ilus, tab
Article in Spanish | LILACS, UNISALUD, BINACIS | ID: biblio-1552204

ABSTRACT

Antecedentes. El valor pronóstico de una ergometría positiva en el contexto de imágenes tomográficas de perfusión miocárdica de estrés y reposo (SPECT) normales no está bien establecido. Objetivos. Documentar la incidencia de infarto, muerte y revascularización coronaria en pacientes con una ergometría positiva de riesgo intermedio e imágenes de perfusión SPECT normales, y explorar el potencial valor del puntaje de riesgo de Framingham en la estratificación pronóstica de estos pacientes. Métodos. Cohorte retrospectiva integrada por pacientes que habían presentado síntomas o hallazgos electrocardiográficos compatibles con enfermedad arterial coronaria durante la prueba de esfuerzo, con criterios de riesgo intermedio en la puntuación de Duke y perfusión miocárdica SPECT normal. Fueron identificados a partir de la base de datos del laboratorio de cardiología nuclear del Instituto de Cardiología y Cirugía Cardiovascular de la ciudad de Posadas, Argentina. Resultados. Fueron elegibles 217 pacientes. El seguimiento fue de 3 1,5 años. La sobrevida libre de eventos (muerte,infarto de miocardio no fatal, angioplastia coronaria o cirugía de bypass de arteria coronaria) a uno, tres y cinco años fue significativamente menor (Log-rank test, p= 0,001) en el grupo con puntaje de Framingham alto o muy alto (77, 71y 59 %, respectivamente) que en el grupo de puntaje bajo o intermedio (89, 87 y 83 %). Tomando como referencia a los pacientes con riesgo bajo en el puntaje de Framingham, luego de ajustar por edad, sexo y puntaje de Duke, los pacientes categorizados en los estratos alto y muy alto riesgo del puntaje de Framingham presentaron una incidencia del evento combinado cercana al triple (hazard ratio [HR] 2,81; intervalo de confianza [IC] del 95 % 0,91 a 8,72; p= 0,07 y HR 3,61;IC 95 % 1,23 a 10,56; p= 0,019 respectivamente). Conclusiones. La estimación de riesgo con el puntaje de Framingham sería de ayuda en la estratificación pronóstica de los pacientes con ergometría positiva y SPECT normal. (AU)


Background. The prognostic value of positive exercise testing with normal SPECT myocardial perfusion imaging is not well established. Objectives. To document the incidence of infarction, death, and coronary revascularization in patients with a positive intermediate-risk exercise test and normal SPECT perfusion images and to explore the potential value of the Framingham Risk Score in the prognostic stratification of these patients. Methods. A retrospective cohort comprised patients who presented symptoms or electrocardiographic findings compatible with coronary artery disease during the stress test, with intermediate risk criteria in the Duke score and normal SPECT myocardial perfusion. They were identified from the database of the nuclear cardiology laboratory of the Instituto de Cardiología y Cirugía Cardiovascular of Posadas, Argentina. Results. 217 patients were eligible. Follow-up was 3 1.5 years. Event-free survival (death, non-fatal myocardial infarction, coronary angioplasty, or coronary artery bypass surgery) at one, three, and five years was significantly lower (Log-ranktest, p: 0.001) in the group with a score of Framingham high or very high (77, 71 and 59 %, respectively) than in the lowor intermediate score group (89, 87 and 83 %). Taking as reference the low-risk patients in the Framingham score, after adjusting for age, sex, and Duke score, the patients categorized in the high-risk and very high-risk strata showed about three times higher incidence of the combined event (hazard ratio [HR] 2.81; 95 % confidence interval [CI] 0.91 to 8.72;p=0.07 and HR 3.61; 95 % CI 1.23 to 10.56; p=0.019 respectively). Conclusions. Risk estimation with the Framingham score would be helpful in the prognostic stratification of patients with positive exercise testing and normal SPECT. (AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Prognosis , Myocardial Infarction/prevention & control , Myocardial Infarction/diagnostic imaging , Survival Analysis , Tomography, Emission-Computed, Single-Photon , Incidence , Retrospective Studies , Risk Factors , Sensitivity and Specificity , Ergometry , Risk Assessment/methods , Exercise Test , Myocardial Perfusion Imaging , Percutaneous Coronary Intervention , Myocardial Infarction/mortality
3.
Article in Spanish | LILACS, UNISALUD, BINACIS | ID: biblio-1552286

ABSTRACT

La evaluación de la perfusión miocárdica con SPECT combina una prueba de esfuerzo (ergometría o estrés farmacológico) junto a imágenes de perfusión con radioisótopos. Este estudio es útil para establecer el diagnóstico de enfermedad arterial coronaria, estratificar el riesgo de infarto y tomar decisiones terapéuticas. Un resultado normal aporta un alto valor predictivo negativo, es decir, una muy baja probabilidad de que el paciente presente eventos cardiovasculares. El hallazgo de signos de isquemia en la ergometría podría poner en jaque el valor predictivo negativo de una perfusión normal. En presencia de este resultado, el paso siguiente es evaluar los predictores de riesgo en la ergometría, el riesgo propio del paciente en función de los antecedentes clínicos y el puntaje cálcico coronario, cuando este se encuentra disponible. Ante la presencia concomitante de otros marcadores de riesgo se sugiere completar la evaluación con un estudio anatómico.El uso de nuevas tecnologías podría mejorar la precisión en la predicción de eventos. (AU)


Assessment of myocardial perfusion with SPECT combines a stress test (ergometry or pharmacological stress) with radioisotope perfusion imaging. This test is helpful to diagnose coronary artery disease, stratify the risk of heart attack, and make therapeutic decisions. A normal result provides a high negative predictive value; therefore, the probability of cardiovascular events is very low. Signs of ischemia on an ergometry could jeopardize the negative predictive value of normal perfusion. In this clinical setting, the next step is to evaluate the risk predictors in the stress test, the individual risk based on the clinical history, and the coronary calcium score when available. Given the simultaneous presence of other risk markers,completing the evaluation with an anatomical study is suggested. The use of new technologies could improve the accuracy of event prediction. (AU)


Subject(s)
Humans , Tomography, Emission-Computed, Single-Photon , Ergometry , Myocardial Ischemia/diagnostic imaging , Risk Assessment/methods , Myocardial Perfusion Imaging , Myocardial Infarction/prevention & control , Prognosis , Survival , Coronary Artery Disease/diagnostic imaging , Sensitivity and Specificity , Exercise Test , Clinical Decision-Making
4.
Rev. bras. ortop ; 58(6): 912-916, 2023. tab
Article in English | LILACS | ID: biblio-1535622

ABSTRACT

Abstract Objectives To analyze the lower limb strength in both untreated and surgically treated adolescent idiopathic scoliosis (AIS) patients and examine its correlation with the distance covered in a six-minute walking test (6MWT). Methods A total of 88 participants (n = 30 pre-surgery AIS patients, n = 30 postsurgical AIS patients, and n = 28 control) underwent a 6MWT and a muscle strength assessment. The lower limb strength was measured at the knee joint using the knee extension (KE) and knee flexion (KF) peak torque (PT) measurements. Results The control group covered a greater distance in the TC6 compared to both the pre-surgical (534 ± 67 m) and post-surgical (541 ± 69 m) groups, with a distance of 612 ± 70 m (p < 0.001). No differences were observed in KE PT (pre: 2.1 ± 0.63, post: 2.1 ± 0.7, control: 2.2 ± 0.7 Nm.kg-1, p = 0.67) or KF PT (pre: 1.0 ± 0.3, post: 1.1 ± 0.3, control: 1.1 ± 0.5 Nm.kg-1, p = 0.46). A moderate positive correlation was observed between KE PT and 6MWT distance (r = 0.53, p < 0.001), as well as a low positive correlation for KF PT (r = 0.37, p = 0.003) with 6MWT distance. Conclusion This study highlights the importance of lower limb maximal strength in the functionality of AIS patients. Our findings suggest that exercise programs aimed at enhancing lower limb strength, especially the KE, could improve the walking capacity of AIS patients. These results provide useful information for designing purposeful exercise programs for AIS patients with walking deficits.


Resumo Objetivos Analisar a força dos membros inferiores em pacientes com escoliose idiopática do adolescente (EIA) submetidos ou não ao tratamento cirúrgico e examinar sua correlação com a distância percorrida em um teste de caminhada de seis minutos (TC6). Métodos Um total de 88 participantes (n = 30 pacientes com EIA pré-operatório, n = 30 pacientes com EIA pós-operatório e n = 28 controles) foram submetidos ao 6MWT e à avaliação da força muscular. A força dos membros inferiores foi medida na articulação do joelho usando os valores de pico de torque (PT) de extensão do joelho (EJ) e flexão do joelho (FJ). Resultados O grupo controle percorreu uma distância maior no TC6 em comparação aos grupos pré-operatório (534 ± 67 m) e pós-operatório (541 ± 69 m), com distância de 612 ± 70 m (p < 0,001). Não foram observadas diferenças em PT EJ (pré: 2,1 ± 0,63, pós: 2,1 ±0,7, controle: 2,2±0,7 Nm.kg-1, p = 0,67) ou PT FJ (pré: 1,0±0,3, pós: 1,1 ±0,3, controle: 1,1 ±0,5 Nm.kg-1, p = 0,46). Houve uma correlação positiva moderada entre PT EJ e a distância do TC6 (r = 0,53, p<0,001), assim como uma correlação positiva baixa entre PT FJ (r = 0,37, p = 0,003) e a distância do TC6. Conclusão Este estudo destaca a importância da força máxima dos membros inferiores na funcionalidade de pacientes com EIA. Nossos achados sugerem que programas de exercícios destinados a aumentar a força dos membros inferiores, especialmente de EJ, podem melhorar a capacidade de caminhada de pacientes com EIA. Esses resultados fornecem informações úteis para o projeto de programas de exercícios intencionais para pacientes com EIA e déficits de marcha.


Subject(s)
Humans , Male , Female , Adolescent , Outcome and Process Assessment, Health Care , Scoliosis/surgery , Exercise Test , Muscle Strength
5.
Rev. bras. med. esporte ; 29: e2022_0166, 2023. tab, graf
Article in English | LILACS | ID: biblio-1394840

ABSTRACT

ABSTRACT Introduction: Physical training for the elderly is extremely popular. However, there is a lack of analysis on sports injuries in the elderly. Objective: Study the analysis of movement in sports training techniques and preventing sports injuries in the elderly. Methods: Participating in a 15-minute running and warm-up activity before using the standard FMS test kit, they followed seven test movements, each repeated three times; they did so during six weeks of training based on the recommendations for the prevention of sports injuries presented in this paper. Results: Among the 14 elderly subjects with a total FMS score <14 points, most functional motor scores were 15-16 points, of which 19 points were high, and 9 points were low. In the intervention based on the perspective of sports injuries, the FMS measurement value of the elderly was much better than before, and the evaluation of the technical analysis of movement after the correction was significantly higher than before. Conclusion: The prevention of sports injuries proposed in this paper can effectively help the elderly to prevent sports injuries. This paper considers the FMS trial design as an example for analyzing movements in sports training of the elderly and formulating standards. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.


RESUMO Introdução: O treinamento físico em idosos é extremamente popular, entretanto, carece de análise sobre as lesões esportivas em idosos. Objetivo: Estudar a análise do movimento nas técnicas de treinamento esportivo e a prevenção de lesões esportivas em idosos. Métodos: Participando de uma atividade de 15 minutos de corrida e aquecimento antes de utilizar o kit de teste padrão FMS, seguiram-se sete movimentos de teste, cada um deles repetidos 3 vezes; fizeram-no durante seis semanas de treinamento com base nas recomendações de prevenção de lesões esportivas apresentadas neste trabalho. Resultados: Entre os 14 sujeitos idosos com pontuação total de FMS <14 pontos, a maioria das pontuações motoras funcionais foram de 15-16 pontos, dos quais 19 pontos foram altos e 9 pontos foram baixos. Na intervenção baseada sob a ótica das lesões esportivas, o valor de medição FMS dos idosos foi muito melhor do que anteriormente, e a avaliação da análise técnica do movimento após a correção foi significativamente maior do que aquela antes da correção. Conclusão: A prevenção de lesões esportivas proposta neste trabalho pode efetivamente ajudar os idosos a prevenir as lesões esportivas. Este documento considera o projeto de ensaio do FMS como um exemplo para analisar os movimentos no treinamento esportivo das pessoas idosas e para formular padrões. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.


RESUMEN Introducción: El entrenamiento físico en las personas mayores es muy popular, sin embargo, hay una falta de análisis sobre las lesiones deportivas en las personas mayores. Objetivo: Estudiar el análisis del movimiento en las técnicas de entrenamiento deportivo y la prevención de lesiones deportivas en las personas mayores. Métodos: Participando en una actividad de carrera y calentamiento de 15 minutos antes de utilizar el kit de prueba estándar de FMS, se siguieron siete movimientos de prueba, cada uno repetido 3 veces; lo hicieron durante seis semanas de entrenamiento basado en las recomendaciones para la prevención de lesiones deportivas presentadas en este trabajo. Resultados: Entre los 14 sujetos de edad avanzada con una puntuación total de FMS <14 puntos, la mayoría de las puntuaciones motoras funcionales eran de 15-16 puntos, de los cuales 19 puntos eran altos y 9 puntos eran bajos. En la intervención basada en la perspectiva de las lesiones deportivas, el valor de medición de la FMS de los ancianos fue mucho mejor que antes, y la evaluación del análisis técnico del movimiento después de la corrección fue significativamente mayor que antes de la corrección. Conclusión: La prevención de las lesiones deportivas propuesta en este artículo puede ayudar eficazmente a las personas mayores a prevenir las lesiones deportivas. Este documento considera el diseño de la prueba FMS como un ejemplo para analizar los movimientos en el entrenamiento deportivo de las personas mayores y para formular normas. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.


Subject(s)
Humans , Male , Female , Aged , Athletic Injuries/prevention & control , Aged , Exercise , Exercise Test , Physical Functional Performance , Movement/physiology
6.
Cienc. act. fis. (Talca, En linea) ; 23(2): 1-12, dez. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1421097

ABSTRACT

Objetivos: la valoración de la tolerancia al ejercicio es clave para prescribir ejercicio en candidatos a cirugía bariátrica. El test de lanzadera (TL) se ha propuesto para este objetivo. Sin embargo, la evidencia que describe el rendimiento y respuesta fisiológica asociados a esta prueba en dicha población es escasa. El objetivo de este estudio fue describir la respuesta fisiológica a la realización del TL en candidatos a cirugía bariátrica. Métodos: este estudio transversal incluyó a 56 participantes. Se midieron factores antropométricos como la edad, peso, estatura y circunferencia de cintura, así como el nivel de actividad física espontáneo. Se valoró el rendimiento en el TL en metros, la respuesta fisiológica asociada en términos de frecuencia cardiaca de reserva (FCR) utilizada, presión arterial sistólica y diastólica, oximetría de pulso, sensación subjetiva al esfuerzo (SSE) y de fatiga de extremidades inferiores, antes y después del TL. Resultados: todos los participantes completaron la prueba sin complicaciones. Caminaron una mediana de 465 metros, equivalente al 61% de la distancia esperada. Utilizaron un 56% de la FCR, mientras que la SSE y fatiga de extremidades inferiores alcanzó valores 7/10 y 6/10 respectivamente. Fueron observadas asociaciones significativas entre el rendimiento en el TL vs factores antropométricos e indicadores de respuesta fisiológica. Conclusión: el TL es una prueba segura para valorar la tolerancia al esfuerzo en candidatos a cirugía bariátrica, la cual induce respuestas fisiológicas asociadas a intensidades moderadas. Se sugiere incluir esta prueba para la valoración de la condición física de estos sujetos.


Objective: Exercise tolerance measurement is key for exercise prescription in bariatric surgery candidates. Thus, the incremental shuttle walking test (ISWT) has been proposed as a useful tool for this purpose. However, reports describing the performance, and related physiological response, in candidates to bariatric surgery are scarce. Therefore, the aim of this study was to describe the physiological response of bariatric surgery candidates to the ISWT. Methods: This cross-sectional study included 56 participants. Anthropometric factors such as age, weight, height, and waist circumference were measured, as well as their spontaneous physical activity levels. Their ISWT performance was recorded, as well as the percentage of heart rate reserve used during the test, systolic and diastolic pressure, pulse oximetry, perceived exertion scale, and lower extremities fatigue, both before and after the ISWT. Results: All participants completed the test without complications. They walked a median of 465 meters, 61% of the expected distance. Heart rate reserve utilization reached 56%, while the perceived exertion rate and lower extremities fatigue reached 7/10 and 6/10, respectively. Moreover, significant associations between the ISWT performance vs anthropometric factors and physiological response outcomes were found. Conclusion: The ISWT is a safe and useful tool to assess exercise tolerance in bariatric surgery candidates, which induces physiological responses associated to moderate effort intensities. We suggest including the ISWT when assessing the physical performance of bariatric surgery candidates.


Objetivo: A medida da tolerância ao exercício é fundamental para a prescrição do exercício em candidatos à cirurgia bariátrica. Assim, o teste incremental de caminhada em vaivém (ISWT) tem sido proposto como uma ferramenta útil para este fim. No entanto, são escassos os relatos que descrevem o desempenho e a resposta fisiológica relacionada em candidatos à cirurgia bariátrica. Portanto, o objetivo deste estudo foi describir a resposta fisiológica do ISWT em candidatos à cirurgia bariátrica. Métodos: Este estudo transversal incluiu 56 participantes. Fatores antropométricos como idade, peso, altura, circunferência da cintura foram medidos, assim como os níveis de atividade física espontânea. O desempenho do ISWT foi registrado, assim como a porcentagem de reserva de frequência cardíaca utilizada durante o teste, pressão sistólica e diastólica, oximetria de pulso, escala de esforço percebido e fadiga de membros inferiores, tanto antes quanto após o ISWT. Resultados: Todos os participantes completaram o teste sem intercorrências. Eles caminharam uma mediana de 465 metros, o equivalente a 61% da distância esperada. A utilização de reserva de frequência cardíaca atingiu 56%, enquanto a taxa de esforço percebido e fadiga de membros inferiores atingiram 7/10 e 6/10, respectivamente. Além disso, foram encontradas associações significativas entre o desempenho do ISWT versus fatores antropométricos e os resultados da resposta fisiológica. Conclusão: O ISWT é uma ferramenta segura e útil para avaliar a tolerância ao exercício em candidatos à cirurgia bariátrica, que induz respostas fisiológicas associadas a intensidades moderadas de esforço. Sugerimos incluir o ISWT para avaliar o desempenho físico dos candidatos à cirurgia bariátrica.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Bariatric Surgery , Physical Exertion/physiology , Walk Test , Cross-Sectional Studies , Exercise Tolerance , Exercise Test
7.
Cienc. act. fis. (Talca, En linea) ; 23(2): 1-16, dez. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1421100

ABSTRACT

Objetivo: el objetivo de este estudio es describir el perfil de las variables del EIMP entre las dos posiciones de juego y determinar las posibles asociaciones con las características antropométricas y las cualidades físicas de un grupo de jugadores Rugby amateurs chilenos. Hipótesis: es por eso por lo que podemos plantear como hipótesis la existencia de asociaciones entre las variables de EIMP y las cualidades físicas de los jugadores de RU. Diseño metodológico: este estudio tiene un diseño de cohorte observacional, descriptivo y correlacional. Se investigó la asociación existente entre las variables de EIMP con las pruebas físicas y las variables antropométricas. Fueron evaluados treinta y dos jugadores de rugby varones de nivel amateurs chilenos (promedio ( DE, edad, 23,3 ( 5,4 años). Resultados: para la variable Masa Muscular se encontraron asociaciones grandes (r = 0.53) (p = 0.001) con la FM y asociaciones moderadas (r = 0,48) (r = 0,47) (r = 0,44) (r = 0,46) con F50, F100, F150 y F200 respectivamente. También se pueden observar las asociaciones grandes (R2 = 0,305) (R2 = 0,297) (R2 = 0,267) entre 1RM PB y F200, F100 y F150, respectivamente. Conclusión: en conclusión, este estudio puede demostrar la existencia de asociaciones estadísticamente significativas entre algunas de las variables antropométricas y físicos con las variables de Fuerza de EIMP en jugadores de RU amateurs chilenos.


OBJECTIVE: The objective of this study is to describe the profile of the EIMP variables between two playing positions and to determine its possible associations with anthropometric characteristics and physical qualities of a group of Chilean amateur rugby players. HYPOTHESIS: There are associations between the EIMP variables and the physical qualities of UR players. METHODOLOGICAL DESIGN: This study has an observational, descriptive and correlational cohort design. The association between the EIMP variables, from the physical tests, and the anthropometric variables was investigated. Thirty-two Chilean amateur-level male rugby players were evaluated (mean ( SD, age, 23.3 ( 5.4 years). RESULTS: For the Muscle Mass variable, large associations were found (r=0.53) (p=0.001) to FM, and moderate associations (r=0.48) (r=0.47) (r=0.44) (r =0.46) to F50, F100, F150, and F200 respectively. Large associations (R2=0.305) (R2=0.297) (R2=0.267) between 1RM PB and F200, F100, and F150, respectively, can also be observed. CONCLUSION: In conclusion, this study can demonstrate the existence of statistically significant associations between some of the anthropometric and physical variables and the EIMP Strength variables in Chilean amateur UR players.


OBJETIVO: O objetivo deste estudo é descrever o perfil das variáveis EIMP entre as duas posições de jogo e determinar as possíveis associações com as características antropométricas e qualidades físicas de um grupo de jogadores amadores de rugby chilenos. HIPÓTESE: É por isso que podemos hipotetizar a existência de associações entre as variáveis do EIMP e as qualidades físicas dos jogadores do RU. DESENHO METODOLÓGICO: Este estudo tem um desenho de coorte observacional, descritivo e correlacional. Investigou-se a associação entre as variáveis do EIMP com os testes físicos e as variáveis antropométricas. Trinta e dois jogadores de rugby masculinos de nível amador chileno foram avaliados (média ( DP, idade, 23,3 ( 5,4 anos). RESULTADOS: Para a variável Massa Muscular foram encontradas grandes associações (r=0,53ejercicio y cualidades físicos) (r=0,47) (r=0,44) (r=0,46) com F50, F100, F150 e F200 respectivamente. Grandes associações (R2=0,305) (R2=0,297) (R2=0,267) entre 1RM PB e F200, F100 e F150 respebaloncestotambém podem ser observadas. CONCLUSÃO: Em conclusão, este estudo pode demonstrar a existência de associações estatisticamente significativas entre algumas das variáveis antropométricas e físicas com as variáveis EIMP Força em jogadores amadores do RU chilenos.


Subject(s)
Humans , Male , Adult , Young Adult , Anthropometry , Exercise Test/methods , Muscle Strength/physiology , Rugby/physiology , Thigh/physiology , Exercise , Confidence Intervals , Regression Analysis , Analysis of Variance , Isometric Contraction/physiology
8.
Int. j. cardiovasc. sci. (Impr.) ; 35(3): 354-363, May-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1375637

ABSTRACT

Abstract Background: Different immune mechanisms of myocardial damage involved in the pathophysiology of Chagas disease coexist with high titers of autoantibodies induced by T. cruzi . There are few studies in the literature about the adaptive role of anti-β1 and anti-M2 antibodies in chronic Chagas cardiomyopathy (CCC). Objectives: To evaluate the association between anti-β1 and anti-M2 antibodies with heart rate variability (HRV) parameters on 24h Holter monitoring and the rate-pressure product (RPP) on cardiopulmonary exercise testing (CPET). Methods: Anti-β1 and anti-M2 antibody titers were measured by enzyme-linked immunosorbent assay (ELISA) in 64 patients affected by CCC. Analysis of HRV was performed through the time-domain indices NNs, mean NN, SDNN, SDANN, SDNN index, NNNs, RMSSD, and pNN50. Spearman's correlation coefficient was used to assess the association between antibody titers and numerical variables. The Mann-Whitney test was used for comparison between two groups. Multiple linear regression was used to identify independent variables capable of explaining anti-β1 and anti-M2 antibody titers at the 5% significance level. Results: On 24h Holter, during the period of greatest parasympathetic activation (2:00-6:00 a.m.), an inverse association was found between anti-β1 titers and SDNN (rs=-0.13, p =0.041, n=43), as well as a direct association between anti-M2 titers and SDANN ( r s=0.317, p =0.039, n=43). Regarding CPET variables, anti-β1 titers were directly associated with RPP (rs=0.371, p =0.005, n=56). The subgroup of patients with a normal chronotropic response showed higher anti-β1 titers than the subgroup with an impaired response (p=0.023). RPP was an independent explanatory variable for anti-β1 titers, although with a low coefficient of determination (R2=0.147). Conclusion: The findings of this study suggest that, in patients with CCC, anti-β1 and anti-M2 antibodies may affect HRV parameters. RPP was directly associated with higher anti-β1 titers.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Autonomic Nervous System/physiology , Chagas Cardiomyopathy/physiopathology , Receptors, Adrenergic, beta-1/physiology , Receptor, Muscarinic M2/physiology , Chronic Disease , Cross-Sectional Studies , Antibodies, Bispecific , Exercise Test
9.
Int. j. cardiovasc. sci. (Impr.) ; 35(3): 304-315, May-June 2022. tab, graf
Article in English | LILACS | ID: biblio-1375639

ABSTRACT

Abstract Background Obesity and overweight in childhood can increase the risk of developing cardiovascular disease throughout live. Objectives This study provides an update of a meta-analysis of randomized clinical trials (RCT) published in 2014, to assess the effects of physical activity interventions on preventing cardiovascular risk factors in childhood. Methods This update combines data from the previous search with new data obtained from June 2013 to June 2020. Searches were performed on PubMed, EMBASE and Cochrane CENTRAL. The RCTs enrolled used interventions with physical activity longer than six months in school children aged 6-12 years, and evaluated body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) and high-density lipoprotein (HDL) levels. Data analysis was performed using a random-effects model and a P value <0.05 was considered statistically significant. Results A total of 28,603 articles were retrieved, and 17 RCTs (11,952 subjects) were included. Physical activity interventions were associated with reduction in SBP [−2.11mmHg (95%CI −3.67, −0.54), I243%], DBP [−2.08mmHg (95%CI −3.68, −0,49), I265%] and TG [-0.08mmol/L (95% CI -0.13, -0.03), I20%], and increase in TC [0.17mmol/L (95%CI 0.04, 0.30), I20%]. However, the interventions were not associated with reductions in BMI [−0.03 kg/m2 (95%CI −0.17, 0.10), I20%]. Conclusion This update confirms and reinforces the beneficial effects of physical activity intervention in reducing systolic and diastolic blood pressure and TG levels.


Subject(s)
Humans , Male , Female , Child , Cardiovascular Diseases/prevention & control , Exercise , Heart Disease Risk Factors , Sports , Students , Exercise Test , Pediatric Obesity , Physical Conditioning, Human
10.
Rev. med. vet. zoot ; 69(1): 33-39, ene.-abr. 2022. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1389165

ABSTRACT

RESUMEN Se analizaron los niveles de lactato sérico y de frecuencia cardiaca (FC) en 15 perros clinicamente sanos que fueron sometidos a pruebas de esfuerzo en trotadora motorizada, buscando verificar un grado de fatiga muscular frente a una prueba de esfuerzo intenso. Se consideraron pacientes con morfologia craneana de tipo braquicefálico, mesocefálico y dolicocefálico. Las mediciones séricas de lactato fueron conseguidas por medio de un medidor portátil, mientras que las frecuencias cardiacas se obtuvieron a través de un oximetro portátil a los tiempos 0, 10, 20 y 30 minutos, en los diferentes momentos de esfuerzo fisico en la trotadora motorizada, la cual fue adaptada en su inclinación en 15% y a un máximo de velocidad de 10 km/h. Las medias de los niveles séricos entre perros mesocefálicos y dolicocefálicos fueron significativas, a diferencia de los perros braquicefálicos los cuales resultaron no significativos. Las medias de las frecuencias cardiacas no tuvieron diferencia significativa bajo un 95% de confianza.


ABSTRACT Serum lactate and heart rate (HR) levels were analyzed in 15 clinically healthy dogs that were subjected to stress tests on a motorized treadmill, seeking to verify a degree of muscle fatigue compared to an intense exercise test. Patients with brachycephalic, mesocephalic and dolichocephalic type cranial morphology were considered. Serum lactate measurements were procured by means of a portable meter, while heart rates were obtained through a portable oximeter at the times 0, 10, 20, and 30 minutes at different moments of physical effort on the motorized treadmill, which was adapted in its inclination by 15% and at a maximum speed of 10 km/h. Mean serum levels between mesocephalic and dolichocephalic dogs were significant, unlike brachycephalic dogs, which were not significant. The mean heart rates did not have a significant difference under 95% confidence.


Subject(s)
Biomarkers , Dogs , Exercise Test , Lactic Acid , Serum , Fatigue , Heart Rate
11.
Arq. bras. cardiol ; 118(3): 565-575, mar. 2022. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1364343

ABSTRACT

Resumo Fundamento Pacientes com anemia falciforme (AF) têm risco aumentado de complicações cardiovasculares. O teste ergométrico é usado como marcador de prognóstico em uma série de doenças cardiovasculares. Entretanto, há uma escassez de evidências sobre exercícios em pacientes com AF, especialmente em relação à sua segurança, viabilidade e possível função prognóstica. Objetivos Usamos o teste em esteira máximo para determinar a segurança e a viabilidade do teste ergométrico em pacientes com AF. Além disso, os fatores associados à duração do exercício, bem como o impacto das alterações causadas pelo exercício em resultados clínicos, também foram avaliados. Métodos 113 pacientes com AF que passaram pelo teste ergométrico e por uma avaliação cardiovascular abrangente incluindo um ecocardiograma e os níveis do peptídeo natriurético do tipo B (BNP). O desfecho de longo prazo foi uma combinação de eventos incluindo morte, crises álgicas graves, síndrome torácica aguda ou internações hospitalares por outras complicações associadas â doença falciforme. A análise de regressão de Cox foi realizada para identificar as variáveis associadas ao resultado. Um p valor <0,05 foi considerado estatisticamente significativo. Resultados A média de idade foi de 36 ± 12 anos (intervalo, 18-65 anos), e 62 pacientes eram do sexo feminino (52%). A presença de alterações isquêmicas ao esforço e resposta pressórica anormal ao exercício foram detectadas em 17% e 9 % da´população estudada respectivamente. Dois pacientes apresentaram crise álgica com necessidade de internação hospitalar no período de 48 horas da realização do exame. Fatores associados à duração do exercício foram idade, sexo, velocidade máxima de regurgitação tricúspide (RT), e relação E/e', após a padronização quanto aos marcadores da gravidade da doença. Durante o período médio de acompanhamento de 10,1 meses (variando de 1,2 a 26), 27 pacientes (23%) apresentaram desfechos clínicos adversos. Preditores independentes de eventos adversos foram a concentração de hemoglobina, velocidade do fluxo transmitral tardio (onda A), e a resposta da PA ao exercício. Conclusões A realização de testes ergométricos em pacientes com AF, clinicamente estáveis, é viável. A duração do exercício estava associada à função diastólica e a pressão arterial pulmonar. A resposta anormal da PA foi um preditor independente de eventos adversos.


Abstract Background Patients with sickle cell disease (SCD) are at increased risk for cardiovascular complications. Exercise testing is used as a prognostic marker in a variety of cardiovascular diseases. However, there is a lack of evidence on exercise in SCD patients, particularly regarding its safety, feasibility, and possible prognostic role. Objectives We used the maximal treadmill test to determine safety and feasibility of the exercise testing in SCD patients. Additionally, the factors associated with exercise duration, as well as the impact of exercise-induced changes on clinical outcome, were also assessed. Methods One-hundred thirteen patients with SCD, who underwent exercise testing, were prospectively enrolled. A comprehensive cardiovascular evaluation, including echocardiography and B-type natriuretic peptide (BNP) levels, were obtained. The long-term outcome was a composite endpoint of death, severe acute painful episodes, acute chest syndrome, or hospitalization for other SCD-related complications. Cox regression analysis was performed to identify the variables associated with the outcome. A p-value<0.05 was considered to be statistically significant. Results The mean age was 36 ± 12 years (range, 18-65 years), and 62 patients were women (52%). Ischemic electrocardiogram and abnormal blood pressure (BP) response to exercise were detected in 17% and 9%, respectively. Two patients experienced pain crises within 48 hours that required hospitalization. Factors associated with exercise duration were age, sex, tricuspid regurgitation (TR) maximal velocity, and E/e' ratio, after adjustment for markers of disease severity. During the mean follow-up of 10.1 months (ranging from 1.2 to 26), the endpoint was reached in 27 patients (23%). Independent predictors of adverse events were hemoglobin concentration, late transmitral flow velocity (A wave), and BP response to exercise. Conclusions Exercise testing in SCD patients who were clinically stable is feasible. Exercise duration was associated with diastolic function and pulmonary artery pressure. Abnormal BP response was an independent predictor of adverse events.


Subject(s)
Humans , Female , Adult , Young Adult , Exercise Test , Anemia, Sickle Cell/complications , Prognosis , Echocardiography , Feasibility Studies , Middle Aged
13.
Int. j. cardiovasc. sci. (Impr.) ; 35(2): 191-201, Mar.-Apr. 2022. tab, graf
Article in English | LILACS | ID: biblio-1364978

ABSTRACT

Abstract Background Physical Fitness Tests (PFTs) are part of military routines and are usually administered to applicants for the Brazilian corps member, including the civil police. Objective To identify in the literature, scientific articles aimed at assessing physical fitness of police and military personnel in Brazil, using PFTs. Methods This was a systematic review, using the PRISMA systematization, using the following search keywords "police", "military", "physical fitness test" and " PFT", in English and Portuguese. The databases used were ScienceDirect, PubMed, BVS (Lilacs) and Scielo. Only original works performed with police and military personnel in Brazil were selected, through the application of inclusion and exclusion criteria. Results After the screening process, 11 articles were selected from a total of 1,487. Conclusions The data collected from the selected articles suggest that older age is related to a decrease in physical fitness, and better performance in the tests is related to a lower risk of comorbidities. Although high-intensity training improves physical fitness and anthropometric data, it is associated with injury rates; physically active lifestyle is associated with better flexibility.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Physical Fitness , Police , Exercise Test/methods , Military Personnel , Body Weights and Measures , Brazil , Exercise , Comorbidity , Risk Factors , Age Factors , Military Health , Life Style
14.
Int. j. cardiovasc. sci. (Impr.) ; 35(1): 28-36, Jan.-Feb. 2022. graf, tab
Article in English | LILACS, CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1356316

ABSTRACT

BACKGROUND: Exercise tests are an important tool in the investigation of myocardial ischemia. The ramp protocol has gained increasing importance in clinical practice because of the possibility of individualizing its exercise intensity. OBJECTIVE: To assess and compare the sensitivity, specificity, and accuracy of Bruce and ramp protocols for exercise testing in the diagnosis of myocardial ischemia considering myocardial perfusion scintigraphy as the reference standard. Secondary objectives included the assessment of hemodynamic profiles, functional capacity, and the incidence of arrhythmias in each of the protocols. METHODS: Participants underwent exercise testing using the ramp and Bruce protocols, and the tests' diagnostic power was assessed. For testing the difference between data provided by both protocols, we used a paired Student's t-test or Wilcoxon test, depending on the assumption of data normality. The level of significance adopted for all tests was 5%. RESULTS: The ramp protocol showed sensitivity, specificity, and accuracy values of 55.6%, 82.4%, and 76.7%, respectively, whereas the Bruce protocol had results of 77.8%, 64.7%, and 67.4%, respectively. The maximum heart rate and double product at peak exercise were significantly higher in the Bruce protocol (p = 0.043 and p = 0.040, respectively). No differences were observed between the incidence of arrhythmias in both protocols. CONCLUSION: The Bruce protocol presented higher sensitivity for detecting ischemia on the exercise test, while the ramp protocol presented higher specificity and accuracy.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Coronary Artery Disease/diagnosis , Myocardial Ischemia/diagnosis , Exercise Test , Myocardial Perfusion Imaging/methods , Exercise , Predictive Value of Tests , Hemodynamics
15.
Rev. bras. ativ. fís. saúde ; 27: 1-10, fev. 2022.
Article in English | LILACS | ID: biblio-1418222

ABSTRACT

This study aimed to: a) investigate the most common signs and symptoms reported by people infect-ed by the COVID-19, b) compare total time and weekly level of physical activity of people between pre- and post-infection period, and c) examine the association between physical activity levels and signs and symptoms reported during the disease cycle. Twenty-two adult people (14 males and 8 females, mean age 37.9 ± 16.8 years) living in Ribeirão Preto, Brazil participated in this study. Par-ticipants received a positive diagnosis for COVID-19 by PCR. Physical activity and sitting time was assessed using the International Physical Activity Questionnaire. Variables such as body mass index and the clinical condition of the disease (signs and symptoms) were collected. The most frequent signs and symptoms reported by active and inactive individuals, respectively, were loss of taste (77.8% and 25%), headache (66.7% and 25%), coughing (66.7% and 25%), difficulty breathing (61.1% and 25%), and sore throat (61.1% and 75%). A 120-minute reduction (p = 0.010) in the total time of weekly physical activity and a 155-minute reduction (p = 0.003) of weekly moderate physical activity was observed in the pre- and post-diagnostic COVID-19 infection comparison. There was further an association between difficulty breathing and being physically inactive (odds ratio = 0.222; 95%CI: 0.094 ­ 0.527). Our findings suggest that COVID-19 had a negative impact on physical activity and that being physically active may reduce the likelihood of presenting with difficulty breathing if infected with the SARS-CoV-2 and associated disease COVID-19


Este estudo teve como objetivo: a) investigar os sinais e sintomas mais comuns relatados por pessoas infectadas por COVID-19, b) comparar o tempo total e o nível semanal de atividade física das pessoas no período pré e pós-infecção, c) examinar a associação entre os níveis de atividade física e os sinais e sintomas relatados du-rante o ciclo da doença. Participaram deste estudo 22 pessoas (14 do sexo masculino e oito do feminino, idade média 37,9 ± 16,8 anos) residentes na cidade de Ribeirão Preto, Brasil. Todos receberam diagnóstico positivo para COVID-19 via PCR. A atividade física e o tempo sentado foram avaliados por meio do Questionário Internacional de Atividade Física. Variáveis como índice de massa corporal e o quadro clínico da doença (sinais e sintomas), foram coletadas. Os sinais e sintomas mais frequentes foram perda do paladar (77,8% e 25%), dor de cabeça (66,7% e 25%), tosse (66,7% e 25%), dificuldade para respirar (61,1% e 25%) e dor gar-ganta (61,1% e 75%), para indivíduos ativos e inativos, respectivamente. Uma redução de 120 minutos (p = 0,010) no tempo total de atividade física semanal e de 155 minutos (p = 0,003) de atividade física moderada semanal foi observada na comparação pré e pós-diagnóstico por COVID-19. Houve associação entre dificul-dade para respirar e ser fisicamente inativo (odds ratio = 0,222; IC95%: 0,094 ­ 0,527). Nossos resultados sugerem que a COVID-19 teve impacto negativo na atividade física e que pessoas fisicamente ativas podem reduzir a probabilidade de apresentar dificuldade para respirar quando diagnosticadas por COVID-19


Subject(s)
Oxygen Consumption , Reference Values , Employee Performance Appraisal , Exercise Test
16.
Rev. bras. ativ. fís. saúde ; 27: 1-7, fev. 2022.
Article in Portuguese | LILACS | ID: biblio-1418225

ABSTRACT

Este estudo teve como objetivo comparar a avaliação da resistência aeróbia avaliada pelos testes de McArdle e Conconi e associar as medidas indiretas com a percepção subjetiva por meio da Escala de Capacidade Percebida (ECP). Foram recrutados 29 participantes, 17 homens e 12 mulheres, com idades iguais ou maiores de 18 anos da região de São José, Santa Catarina. Após os recrutamentos foram analisados variáveis como sexo, idade, estatura, massa corporal, frequência cardíaca e esforço físico por meio dos testes de banco de McArdle e Conconi, além da capacidade percebida por meio da ECP. A média da pontuação da ECP foi de 9,72 (DP = 1,60). O Índice de Correlação Intraclasse entre os dois testes foi considerando excelente (r = 0,939; p < 0,001). Além disso, ambas análises apresentaram associação com a variável desfecho. No entanto, o poder explicativo da Regressão Linear, considerando como variável independente o VO2max a partir do deste de McArdle foi maior (45,3%). Assim, recomenta-se a utilização da tabela de referência deste teste para identificação do VO2máx a partir da percepção subjetiva pela ECP. Desta forma, a ECP pode ser uma ferramenta valiosa na avaliação, prescrição de exercícios e em estudos epidemiológicos por sua fácil e rápida aplicabilidade em adultos ativos fisicamente


This study aimed to compare the assessment of aerobic resistance evaluated by the McArdle and Conconi tests and to associate the indirect measures with the subjective perception through the Rating of Perceived Capacity (RPC). 29 participants were recruited, 17 men and 12 women, aged 18 years or older from the region of São José-SC. After recruitment, variables such as gender, age, height, body mass, heart rate and physical effort were analyzed using the McArdle and Conconi bench tests, in addition to the perceived capac-ity through the ECP. The mean ECP score was 9.72 (SD = 1.60). The Intraclass Correlation Index between the two tests was considered excellent (r = 0.939; p < 0.001). In addition, both analyses were associated with the outcome variable. However, the explanatory power of Linear Regression, considering VO2max as an independent variable from McArdle's, was higher (45.3%). Thus, it is recommended to use the reference table of this test to identify the VO2max from the subjective perception by the ECP. In this way, ECP can be a valuable tool in the evaluation, exercise prescription and in epidemiological studies due to its easy and quick easy applicability in physically active adults


Subject(s)
Humans , Male , Female , Oxygen Consumption , Reference Values , Employee Performance Appraisal , Evaluation Studies as Topic , Exercise Test
18.
Afr. j. lab. med. (Print) ; 11(1): 1-9, 2022. tables, figures
Article in English | AIM | ID: biblio-1379112

ABSTRACT

Background: The Northern Cape is South Africa's largest province with an HIV prevalence of 7.1% versus a 13.5% national prevalence. CD4 testing is provided at three of five National Health Laboratory Service district laboratories, each covering a 250 km precinct radius. Districts without a local service report prolonged CD4 turn-around times (TAT).Objective: This study documented the impact of a new CD4 laboratory in Tshwaragano in the remote John Taolo Gaetsewe district of the Northern Cape, South Africa.Methods: CD4 test volumes and TAT (total, pre-analytical, analytical, and post-analytical) data for the Northern Cape province were extracted for June 2018 to October 2019. The percentage of CD4 results within the stipulated 40-h TAT cut-off and the median and 75th percentiles of all TAT parameters were calculated. Pre-implementation, samples collected at Tshwaragano were referred to Kimberley or Upington, Northern Cape, South Africa.Results: Pre-implementation, 95.4% of samples at Tshwaragano were referred to Kimberley for CD4 testing (36.3% of Kimberley's test volumes). Only 7.5% of Tshwaragano's total samples were referred post-implementation. The Tshwaragano laboratory's CD4 median total TAT decreased from 24.7 h pre-implementation to 12 h post-implementation (p = 0.003), with >95.0% of results reported within 40 h. The Kimberley laboratory workload decreased by 29.0%, and testing time significantly decreased from 10 h to 4.3 h.Conclusion: The new Tshwaragano CD4 service significantly decreased local TAT. Upgrading existing community laboratories to include CD4 testing can alleviate provincial service load and improve local access, TAT and efficiency in the centralised reference laboratory


Subject(s)
Humans , Male , Female , CD4 Antigens , HIV , Allergy and Immunology , Exercise Test , Hospitals, District , Laboratories , Operations Research
19.
Acta cir. bras ; 37(8): e370804, 2022. tab, graf, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1402974

ABSTRACT

Purpose: Various postoperative protocols have been proposed to improve outcomes and accelerate nerve regeneration. Recently, the use of physical exercise in a post-surgical neurorraphy procedure has shown good results when started early. We experimentally investigated the hypothesis that post-operative exercise speeds up results and improves clinical and morphologic parameters. Methods: Isogenic rats were randomly divided into four groups: 1 SHAM; 2 SHAM submitted to the exercise protocol (EP); 3 Grafting of the sciatic nerve; and 4 Grafting of the sciatic nerve associated with the EP. The EP was based on aerobic activities with a treadmill, with a progressive increase in time and intensity during 6 weeks. The results were evaluated by the sciatic functional index (SFI), morphometric and morphologic analysis of nerve distal to the lesion, and the number of spinal cord motor neurons, positive to the marker Fluoro-Gold (FG), captured retrogradely through neurorraphy. Results: Functional analysis (SFI) did not show a statistical difference between the group grafted with (­50.94) and without exercise (-65.79) after 90 days. The motoneurons count (Spinal cord histology) also showed no diference between these groups (834.5 × 833 respectively). Although functionally there is no difference between these groups, morphometric study showed a greater density (53.62) and larger fibers (7.762) in GRAFT group. When comparing both operated groups with both SHAM groups, all values were much lower. Conclusions: The experimental model that this aerobic treadmill exercises protocol did not modify nerve regeneration after sciatic nerve injury and repair with nerve graft.


Subject(s)
Animals , Rats , Peroneal Nerve , Peroneal Neuropathies/therapy , Exercise Test , Nerve Regeneration , Hypertension/veterinary , Motor Neurons/physiology
20.
Chinese Journal of Cardiology ; (12): 471-479, 2022.
Article in Chinese | WPRIM | ID: wpr-935172

ABSTRACT

Objective: To investigate the postoperative cardiopulmonary fitness of children with congenital heart diseases (CHD). Methods: This is a retrospective study. A total of 136 children after cardiac correction undergoing cardiopulmonary exercise test (CPET) in Shanghai Children's Medical Center from March 1 to June 30, 2021 were selected. According to the surgical procedure, the children were divided into two groups: the biventricular correction group (BV group) (n=75) and single ventricular correction group (SV group) (n=61). The BV group was divided into two subgroups: simple congenital heart disease (S-CHD) group (n=35) and complex congenital heart disease (C-CHD) group (n=40). CPET parameters, including VO2 max, VO2/kg max, VO2/kg@AT, O2/HR max, HRR, PetCO2 max, CI, HRR at 1 min, VE/VCO2 slope, OUES/kg and EOV, were analyzed. CPET parameters of patients underwent different procedure were compared. In the subgroup analysis, CPET parameters of patients in S-CHD group and C-CHD group were compared. The parameters of the BV group were compared with the normal value. Linear correlation analysis was used to identify the correlation between the CPET parameters. Results: A total of 136 children with CHD after surgery were enrolled. The age was (9.4±3.1) (ranged 6.2-16.0) years, and there was 84 (61.8%) male. All the children completed CPET examination safely without experiencing serious circulation abnormalities. Compared with the SV group, the VO2/kg max ((32.6±6.9) ml·kg-1·min-1 vs. (23.5±5.9) ml·kg-1·min-1, P<0.001), O2/HR max ((7.24±2.93) ml/beat vs. (6.35±2.17)ml/beat, P=0.030), HRR at 1 min ((32.5±13.9) beat/min vs. (26.3±12.5) beat/min, P=0.036), OUES/kg (36.9±8.8 vs. 29.7±11.8, P=0.001) were significantly higher, VE/VCO2 slope (29.1±5.20 vs. 35.1±8.0, P<0.001) and incidence of EOV (32.0%(24/75) vs. 57.4%(31/61), P=0.027) were significantly lower in BV group. Compared with the simple CHD subgroup, VE/VCO2 slope and the incidence of EOV were higher, VO2/kg max, O2/HR max, HRR at 1 min and OUES/kg were lower in the complex CHD subgroup (all P<0.05). Cardiopulmonary function parameters of the BV group were lower than the normal value. Linear correlation analysis showed that VO2/kg@AT was strongly correlated with VO2/kg max (r=0.86, P<0.001), VO2/kg max was strongly correlated with OUES/kg (r=0.63, P<0.001), HRR was strongly correlated with CI (r=0.91, P<0.001), and VO2/kg max was strongly correlated with OUES/kg (r=0.63, P<0.001). VE/VCO2 slope was strongly correlated with PetCO2 max (r=1.00, P<0.001). Conclusions: The exercise cardiopulmonary function of children after single ventricular correction is weaker than that of biventricular correction, and the exercise tolerance of children after biventricular correction is lower than that of normal children. Among the children after biventricular correction, the exercise tolerance of children with complex CHD is lower than that of children with simple CHD. Postoperative CPET is of important realistic significance for CHD children.


Subject(s)
Adolescent , Child , Female , Humans , Male , China , Exercise Test/methods , Heart Defects, Congenital/surgery , Oxygen Consumption , Retrospective Studies
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